| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | NBR1 | Thr586 | HNTPVDVtPCMSPLP | phosphorylation down-regulates activity | 24879152 | SIGNOR-261795 |
| GSK3A | NBR1 | Thr586 | HNTPVDVtPCMSPLP | phosphorylation down-regulates activity | 24879152 | SIGNOR-261794 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | phosphorylation up-regulates → | NBR1 PThr586 | phosphorylation down-regulates ⊣ | NBR1 | 24879152 | SIGNOR-261795 |
| GSK3A | phosphorylation up-regulates → | NBR1 PThr586 | phosphorylation down-regulates ⊣ | NBR1 | 24879152 | SIGNOR-261794 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3B | phosphorylation → down-regulates activity | NBR1 | SIGNOR-261795 |
| GSK3A | phosphorylation → down-regulates activity | NBR1 | SIGNOR-261794 |