Entity Details

Name GSK3B_Thr586
ID Q14596
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GSK3BNBR1Thr586HNTPVDVtPCMSPLPphosphorylation
down-regulates activity		24879152SIGNOR-261795
GSK3ANBR1Thr586HNTPVDVtPCMSPLPphosphorylation
down-regulates activity		24879152SIGNOR-261794
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GSK3Bphosphorylation
up-regulates
→
NBR1
PThr586		phosphorylation
down-regulates
⊣		NBR124879152SIGNOR-261795
GSK3Aphosphorylation
up-regulates
→
NBR1
PThr586		phosphorylation
down-regulates
⊣		NBR124879152SIGNOR-261794
Regulator Mechanism/Effect Target SIGNOR-ID
GSK3Bphosphorylation
→
down-regulates activity 		NBR1SIGNOR-261795
GSK3Aphosphorylation
→
down-regulates activity 		NBR1SIGNOR-261794