| Name | ITPR1 |
| ID | Q14643 |
| Role | substrate |
| Enzymatic Domains |
MIR 1 112-166 PROSITE-ProRule
MIR 2 173-223 PROSITE-ProRule
MIR 3 231-287 PROSITE-ProRule
MIR 4 294-373 PROSITE-ProRule
MIR 5 379-435 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | ITPR1 | Ser1598 | RNAARRDsVLAASRD | phosphorylation down-regulates activity | 12529267 | SIGNOR-249996 |
| PRKACA | ITPR1 | Ser1764 | RPSGRREsLTSFGNG | phosphorylation down-regulates activity | 12529267 | SIGNOR-249997 |
| FYN | ITPR1 | Tyr353 | NAQEKMVySLVSVPE | phosphorylation up-regulates | 14761954 | SIGNOR-121795 |
| PRKG1 | ITPR1 | Ser1764 | RPSGRREsLTSFGNG | phosphorylation unknown | 8132598 | SIGNOR-248916 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | phosphorylation up-regulates → | ITPR1 PSer1598 | phosphorylation down-regulates ⊣ | ITPR1 | 12529267 | SIGNOR-249996 |
| PRKACA | phosphorylation up-regulates → | ITPR1 PSer1764 | phosphorylation down-regulates ⊣ | ITPR1 | 12529267 | SIGNOR-249997 |
| FYN | phosphorylation up-regulates → | ITPR1 PTyr353 | phosphorylation up-regulates → | ITPR1 | 14761954 | SIGNOR-121795 |
| PRKG1 | phosphorylation up-regulates → | ITPR1 PSer1764 | phosphorylation down-regulates ⊣ | ITPR1 | 8132598 | SIGNOR-248916 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKACA | phosphorylation → down-regulates activity | ITPR1 | SIGNOR-249996 |
| PRKACA | phosphorylation → down-regulates activity | ITPR1 | SIGNOR-249997 |
| FYN | phosphorylation → up-regulates | ITPR1 | SIGNOR-121795 |
| PRKG1 | phosphorylation → unknown | ITPR1 | SIGNOR-248916 |