Entity Details

Name IKBKE_Thr404
ID Q14653
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
IKBKEIRF3Thr404NSHPLSLtSDQYKAYphosphorylation
up-regulates activity		18440553SIGNOR-178387
TBK1IRF3Thr404NSHPLSLtSDQYKAYphosphorylation
up-regulates activity		18440553SIGNOR-178420
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
IKBKEphosphorylation
up-regulates
→
IRF3
PThr404		phosphorylation
up-regulates
→		IRF318440553SIGNOR-178387
TBK1phosphorylation
up-regulates
→
IRF3
PThr404		phosphorylation
up-regulates
→		IRF318440553SIGNOR-178420
Regulator Mechanism/Effect Target SIGNOR-ID
IKBKEphosphorylation
→
up-regulates activity 		IRF3SIGNOR-178387
TBK1phosphorylation
→
up-regulates activity 		IRF3SIGNOR-178420