Entity Details

Name IRF3_Ser386
ID Q14653
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCIRF3Ser386ARVGGASsLENTVDLphosphorylation
up-regulates activity		35468896SIGNOR-279119
TBK1IRF3Ser386ARVGGASsLENTVDLphosphorylation
up-regulates activity		18440553SIGNOR-178395
IKBKEIRF3Ser386ARVGGASsLENTVDLphosphorylation
up-regulates activity		18440553SIGNOR-178367
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
IRF3
PSer386		phosphorylation
up-regulates
→		IRF335468896SIGNOR-279119
TBK1phosphorylation
up-regulates
→
IRF3
PSer386		phosphorylation
up-regulates
→		IRF318440553SIGNOR-178395
IKBKEphosphorylation
up-regulates
→
IRF3
PSer386		phosphorylation
up-regulates
→		IRF318440553SIGNOR-178367
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
up-regulates activity 		IRF3SIGNOR-279119
TBK1phosphorylation
→
up-regulates activity 		IRF3SIGNOR-178395
IKBKEphosphorylation
→
up-regulates activity 		IRF3SIGNOR-178367