Entity Details

Name IRF3_Ser398
ID Q14653
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
TBK1IRF3Ser398VDLHISNsHPLSLTSphosphorylation
up-regulates activity		18440553SIGNOR-178403
IKBKEIRF3Ser398VDLHISNsHPLSLTSphosphorylation
up-regulates activity		18440553SIGNOR-178375
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
TBK1phosphorylation
up-regulates
→
IRF3
PSer398		phosphorylation
up-regulates
→		IRF318440553SIGNOR-178403
IKBKEphosphorylation
up-regulates
→
IRF3
PSer398		phosphorylation
up-regulates
→		IRF318440553SIGNOR-178375
Regulator Mechanism/Effect Target SIGNOR-ID
TBK1phosphorylation
→
up-regulates activity 		IRF3SIGNOR-178403
IKBKEphosphorylation
→
up-regulates activity 		IRF3SIGNOR-178375