| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTEN | IRF3 | Ser97 | LRLAEDRsKDPHDPH | dephosphorylation up-regulates activity | 32394474 | SIGNOR-277025 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTEN | dephosphorylation down-regulates ⊣ | IRF3 PSer97 | dephosphorylation down-regulates ⊣ | IRF3 | 32394474 | SIGNOR-277025 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTEN | dephosphorylation → up-regulates activity | IRF3 | SIGNOR-277025 |
