Entity Details

Name TBK1_Ser386
ID Q14653
Role residue
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
TBK1IRF3Ser386ARVGGASsLENTVDLphosphorylation
up-regulates activity		18440553SIGNOR-178395
SRCIRF3Ser386ARVGGASsLENTVDLphosphorylation
up-regulates activity		35468896SIGNOR-279119
IKBKEIRF3Ser386ARVGGASsLENTVDLphosphorylation
up-regulates activity		18440553SIGNOR-178367
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
TBK1phosphorylation
up-regulates
→
IRF3
PSer386		phosphorylation
up-regulates
→		IRF318440553SIGNOR-178395
SRCphosphorylation
up-regulates
→
IRF3
PSer386		phosphorylation
up-regulates
→		IRF335468896SIGNOR-279119
IKBKEphosphorylation
up-regulates
→
IRF3
PSer386		phosphorylation
up-regulates
→		IRF318440553SIGNOR-178367
Regulator Mechanism/Effect Target SIGNOR-ID
TBK1phosphorylation
→
up-regulates activity 		IRF3SIGNOR-178395
SRCphosphorylation
→
up-regulates activity 		IRF3SIGNOR-279119
IKBKEphosphorylation
→
up-regulates activity 		IRF3SIGNOR-178367