| Name | MELK |
| ID | Q14680 |
| Role | substrate |
| Enzymatic Domains |
Protein kinase 11-263 PROSITE-ProRule
KA1 602-651 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MELK | MELK | Ser529 | KGAKVFGsLERGLDK | phosphorylation up-regulates | 16216881 | SIGNOR-141018 |
| MELK | MELK | Ser356 | DIKSNNWsLEDVTAS | phosphorylation up-regulates | 16216881 | SIGNOR-140998 |
| MELK | MELK | Thr167 | NKDYHLQtCCGSLAY | phosphorylation up-regulates | 16216881 | SIGNOR-141022 |
| STK11 | MELK | Thr167 | NKDYHLQtCCGSLAY | phosphorylation up-regulates | 16216881 | SIGNOR-141038 |
| MELK | MELK | Ser391 | GAATPRTsQFTKYWT | phosphorylation up-regulates | 16216881 | SIGNOR-141002 |
| MELK | MELK | Thr539 | RGLDKVItVLTRSKR | phosphorylation up-regulates | 16216881 | SIGNOR-141034 |
| MELK | MELK | Ser505 | SPERRCRsVELDLNQ | phosphorylation up-regulates | 16216881 | SIGNOR-141014 |
| MELK | MELK | Ser431 | ENVYTPKsAVKNEEY | phosphorylation up-regulates | 16216881 | SIGNOR-141010 |
| MELK | MELK | Thr494 | TGTDKLMtGVISPER | phosphorylation up-regulates | 16216881 | SIGNOR-141030 |
| MELK | MELK | Ser407 | SNGVESKsLTPALCR | phosphorylation up-regulates | 16216881 | SIGNOR-141006 |
| MELK | MELK | Ser171 | HLQTCCGsLAYAAPE | phosphorylation up-regulates | 16216881 | SIGNOR-140958 |
| MELK | MELK | Thr398 | SQFTKYWtESNGVES | phosphorylation up-regulates | 16216881 | SIGNOR-141026 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MELK | phosphorylation up-regulates → | MELK PSer529 | phosphorylation up-regulates → | MELK | 16216881 | SIGNOR-141018 |
| MELK | phosphorylation up-regulates → | MELK PSer356 | phosphorylation up-regulates → | MELK | 16216881 | SIGNOR-140998 |
| MELK | phosphorylation up-regulates → | MELK PThr167 | phosphorylation up-regulates → | MELK | 16216881 | SIGNOR-141022 |
| STK11 | phosphorylation up-regulates → | MELK PThr167 | phosphorylation up-regulates → | MELK | 16216881 | SIGNOR-141038 |
| MELK | phosphorylation up-regulates → | MELK PSer391 | phosphorylation up-regulates → | MELK | 16216881 | SIGNOR-141002 |
| MELK | phosphorylation up-regulates → | MELK PThr539 | phosphorylation up-regulates → | MELK | 16216881 | SIGNOR-141034 |
| MELK | phosphorylation up-regulates → | MELK PSer505 | phosphorylation up-regulates → | MELK | 16216881 | SIGNOR-141014 |
| MELK | phosphorylation up-regulates → | MELK PSer431 | phosphorylation up-regulates → | MELK | 16216881 | SIGNOR-141010 |
| MELK | phosphorylation up-regulates → | MELK PThr494 | phosphorylation up-regulates → | MELK | 16216881 | SIGNOR-141030 |
| MELK | phosphorylation up-regulates → | MELK PSer407 | phosphorylation up-regulates → | MELK | 16216881 | SIGNOR-141006 |
| MELK | phosphorylation up-regulates → | MELK PSer171 | phosphorylation up-regulates → | MELK | 16216881 | SIGNOR-140958 |
| MELK | phosphorylation up-regulates → | MELK PThr398 | phosphorylation up-regulates → | MELK | 16216881 | SIGNOR-141026 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MELK | phosphorylation → up-regulates | MELK | SIGNOR-141018 |
| MELK | phosphorylation → up-regulates | MELK | SIGNOR-140998 |
| MELK | phosphorylation → up-regulates | MELK | SIGNOR-141022 |
| STK11 | phosphorylation → up-regulates | MELK | SIGNOR-141038 |
| MELK | phosphorylation → up-regulates | MELK | SIGNOR-141002 |
| MELK | phosphorylation → up-regulates | MELK | SIGNOR-141034 |
| MELK | phosphorylation → up-regulates | MELK | SIGNOR-141014 |
| MELK | phosphorylation → up-regulates | MELK | SIGNOR-141010 |
| MELK | phosphorylation → up-regulates | MELK | SIGNOR-141030 |
| MELK | phosphorylation → up-regulates | MELK | SIGNOR-141006 |
| MELK | phosphorylation → up-regulates | MELK | SIGNOR-140958 |
| MELK | phosphorylation → up-regulates | MELK | SIGNOR-141026 |