Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
MELK	MELK	Ser356 View in OncoXplorer	DIKSNNWsLEDVTAS	phosphorylation up-regulates	16216881	SIGNOR-140998

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
MELK	phosphorylation up-regulates →	MELK PSer356	phosphorylation up-regulates →	MELK	16216881	SIGNOR-140998

Regulator	Mechanism/Effect	Target	SIGNOR-ID
MELK	phosphorylation → up-regulates	MELK	SIGNOR-140998