Entity Details

Name TYK2_Tyr693
ID Q14765
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
JAK2STAT4Tyr693TERGDKGyVPSVFIPphosphorylation
up-regulates		16324152SIGNOR-142736
TYK2STAT4Tyr693TERGDKGyVPSVFIPphosphorylation
up-regulates activity		16324152SIGNOR-279303
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
JAK2phosphorylation
up-regulates
→
STAT4
PTyr693		phosphorylation
up-regulates
→		STAT416324152SIGNOR-142736
TYK2phosphorylation
up-regulates
→
STAT4
PTyr693		phosphorylation
up-regulates
→		STAT416324152SIGNOR-279303
Regulator Mechanism/Effect Target SIGNOR-ID
JAK2phosphorylation
→
up-regulates 		STAT4SIGNOR-142736
TYK2phosphorylation
→
up-regulates activity 		STAT4SIGNOR-279303