| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ABL1 | LASP1 | Tyr171 | IPTSAPVyQQPQQQP | phosphorylation up-regulates | 15138294 | SIGNOR-124719 |
| BCR-ABL | LASP1 | Tyr171 | IPTSAPVyQQPQQQP | phosphorylation unknown | 24913448 | SIGNOR-271703 |
| SRC | LASP1 | Tyr171 | IPTSAPVyQQPQQQP | phosphorylation up-regulates activity | 19718473 | SIGNOR-271706 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ABL1 | phosphorylation up-regulates → | LASP1 PTyr171 | phosphorylation up-regulates → | LASP1 | 15138294 | SIGNOR-124719 |
| BCR-ABL | phosphorylation up-regulates → | LASP1 PTyr171 | phosphorylation down-regulates ⊣ | LASP1 | 24913448 | SIGNOR-271703 |
| SRC | phosphorylation up-regulates → | LASP1 PTyr171 | phosphorylation up-regulates → | LASP1 | 19718473 | SIGNOR-271706 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ABL1 | phosphorylation → up-regulates | LASP1 | SIGNOR-124719 |
| BCR-ABL | phosphorylation → unknown | LASP1 | SIGNOR-271703 |
| SRC | phosphorylation → up-regulates activity | LASP1 | SIGNOR-271706 |
