| Name | MYBPC3 |
| ID | Q14896 |
| Role | substrate |
| Enzymatic Domains |
Ig-like C2-type 1 153-256
Ig-like C2-type 2 362-452
Ig-like C2-type 3 453-543
Ig-like C2-type 4 544-633
Ig-like C2-type 5 645-771
Fibronectin type-III 1 774-870 PROSITE-ProRule
Fibronectin type-III 2 872-967 PROSITE-ProRule
Ig-like C2-type 6 971-1065
Fibronectin type-III 3 1068-1163 PROSITE-ProRule
Ig-like C2-type 7 1181-1274 |
View in  |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACG | MYBPC3 | Ser284 | AGGGRRIsDSHEDTG | phosphorylation up-regulates | 20151718 | SIGNOR-163788 |
| PRKACB | MYBPC3 | Ser275 | LSAFRRTsLAGGGRR | phosphorylation up-regulates | 20151718 | SIGNOR-163768 |
| PRKCD | MYBPC3 | Ser284 | AGGGRRIsDSHEDTG | phosphorylation up-regulates | 17075052 | SIGNOR-150351 |
| PKA | MYBPC3 | – | phosphorylation up-regulates | 20151718 | SIGNOR-270128 | |
| PRKACG | MYBPC3 | Ser304 | SLLKKRDsFRTPRDS | phosphorylation up-regulates | 20151718 | SIGNOR-163792 |
| PRKACA | MYBPC3 | Ser311 | SFRTPRDsKLEAPAE | phosphorylation up-regulates | 20151718 | SIGNOR-163764 |
| PRKACB | MYBPC3 | Ser311 | SFRTPRDsKLEAPAE | phosphorylation up-regulates | 20151718 | SIGNOR-163780 |
| PRKACB | MYBPC3 | Ser284 | AGGGRRIsDSHEDTG | phosphorylation up-regulates | 20151718 | SIGNOR-163772 |
| PRKACA | MYBPC3 | Ser284 | AGGGRRIsDSHEDTG | phosphorylation up-regulates | 20151718 | SIGNOR-163756 |
| PRKACB | MYBPC3 | Ser304 | SLLKKRDsFRTPRDS | phosphorylation up-regulates | 20151718 | SIGNOR-163776 |
| PRKACA | MYBPC3 | Ser304 | SLLKKRDsFRTPRDS | phosphorylation up-regulates | 20151718 | SIGNOR-163760 |
| PRKACG | MYBPC3 | Ser311 | SFRTPRDsKLEAPAE | phosphorylation up-regulates | 20151718 | SIGNOR-163796 |
| PRKCD | MYBPC3 | Ser304 | SLLKKRDsFRTPRDS | phosphorylation up-regulates | 17075052 | SIGNOR-150355 |
| PRKACA | MYBPC3 | Ser275 | LSAFRRTsLAGGGRR | phosphorylation up-regulates | 20151718 | SIGNOR-163752 |
| PRKACG | MYBPC3 | Ser275 | LSAFRRTsLAGGGRR | phosphorylation up-regulates | 20151718 | SIGNOR-163784 |
| PRKCD | MYBPC3 | Ser275 | LSAFRRTsLAGGGRR | phosphorylation up-regulates | 17075052 | SIGNOR-150347 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACG | phosphorylation up-regulates → | MYBPC3 PSer284 | phosphorylation up-regulates → | MYBPC3 | 20151718 | SIGNOR-163788 |
| PRKACB | phosphorylation up-regulates → | MYBPC3 PSer275 | phosphorylation up-regulates → | MYBPC3 | 20151718 | SIGNOR-163768 |
| PRKCD | phosphorylation up-regulates → | MYBPC3 PSer284 | phosphorylation up-regulates → | MYBPC3 | 17075052 | SIGNOR-150351 |
| PRKACG | phosphorylation up-regulates → | MYBPC3 PSer304 | phosphorylation up-regulates → | MYBPC3 | 20151718 | SIGNOR-163792 |
| PRKACA | phosphorylation up-regulates → | MYBPC3 PSer311 | phosphorylation up-regulates → | MYBPC3 | 20151718 | SIGNOR-163764 |
| PRKACB | phosphorylation up-regulates → | MYBPC3 PSer311 | phosphorylation up-regulates → | MYBPC3 | 20151718 | SIGNOR-163780 |
| PRKACB | phosphorylation up-regulates → | MYBPC3 PSer284 | phosphorylation up-regulates → | MYBPC3 | 20151718 | SIGNOR-163772 |
| PRKACA | phosphorylation up-regulates → | MYBPC3 PSer284 | phosphorylation up-regulates → | MYBPC3 | 20151718 | SIGNOR-163756 |
| PRKACB | phosphorylation up-regulates → | MYBPC3 PSer304 | phosphorylation up-regulates → | MYBPC3 | 20151718 | SIGNOR-163776 |
| PRKACA | phosphorylation up-regulates → | MYBPC3 PSer304 | phosphorylation up-regulates → | MYBPC3 | 20151718 | SIGNOR-163760 |
| PRKACG | phosphorylation up-regulates → | MYBPC3 PSer311 | phosphorylation up-regulates → | MYBPC3 | 20151718 | SIGNOR-163796 |
| PRKCD | phosphorylation up-regulates → | MYBPC3 PSer304 | phosphorylation up-regulates → | MYBPC3 | 17075052 | SIGNOR-150355 |
| PRKACA | phosphorylation up-regulates → | MYBPC3 PSer275 | phosphorylation up-regulates → | MYBPC3 | 20151718 | SIGNOR-163752 |
| PRKACG | phosphorylation up-regulates → | MYBPC3 PSer275 | phosphorylation up-regulates → | MYBPC3 | 20151718 | SIGNOR-163784 |
| PRKCD | phosphorylation up-regulates → | MYBPC3 PSer275 | phosphorylation up-regulates → | MYBPC3 | 17075052 | SIGNOR-150347 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKACG | phosphorylation → up-regulates | MYBPC3 | SIGNOR-163788 |
| PRKACB | phosphorylation → up-regulates | MYBPC3 | SIGNOR-163768 |
| PRKCD | phosphorylation → up-regulates | MYBPC3 | SIGNOR-150351 |
| PKA | phosphorylation → up-regulates | MYBPC3 | SIGNOR-270128 |
| PRKACG | phosphorylation → up-regulates | MYBPC3 | SIGNOR-163792 |
| PRKACA | phosphorylation → up-regulates | MYBPC3 | SIGNOR-163764 |
| PRKACB | phosphorylation → up-regulates | MYBPC3 | SIGNOR-163780 |
| PRKACB | phosphorylation → up-regulates | MYBPC3 | SIGNOR-163772 |
| PRKACA | phosphorylation → up-regulates | MYBPC3 | SIGNOR-163756 |
| PRKACB | phosphorylation → up-regulates | MYBPC3 | SIGNOR-163776 |
| PRKACA | phosphorylation → up-regulates | MYBPC3 | SIGNOR-163760 |
| PRKACG | phosphorylation → up-regulates | MYBPC3 | SIGNOR-163796 |
| PRKCD | phosphorylation → up-regulates | MYBPC3 | SIGNOR-150355 |
| PRKACA | phosphorylation → up-regulates | MYBPC3 | SIGNOR-163752 |
| PRKACG | phosphorylation → up-regulates | MYBPC3 | SIGNOR-163784 |
| PRKCD | phosphorylation → up-regulates | MYBPC3 | SIGNOR-150347 |