| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GRK2 | SLC9A5 | Thr714 | EESDSSEtEKEDDEG | phosphorylation down-regulates activity | 21296876 | SIGNOR-275502 |
| CSNK2A1 | SLC9A5 | Thr714 | EESDSSEtEKEDDEG | phosphorylation down-regulates activity | 21296876 | SIGNOR-276250 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GRK2 | phosphorylation up-regulates → | SLC9A5 PThr714 | phosphorylation down-regulates ⊣ | SLC9A5 | 21296876 | SIGNOR-275502 |
| CSNK2A1 | phosphorylation up-regulates → | SLC9A5 PThr714 | phosphorylation down-regulates ⊣ | SLC9A5 | 21296876 | SIGNOR-276250 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GRK2 | phosphorylation → down-regulates activity | SLC9A5 | SIGNOR-275502 |
| CSNK2A1 | phosphorylation → down-regulates activity | SLC9A5 | SIGNOR-276250 |