Entity Details

Name NUMA1
ID Q14980
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PLK1NUMA1–phosphorylation
down-regulates activity		30456393SIGNOR-279345
CDK1NUMA1Thr2055
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MAFSILNtPKKLGNSphosphorylation
down-regulates		23921553SIGNOR-194825
TBK1NUMA1–phosphorylation
up-regulates activity		26656453SIGNOR-278432
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
→
NUMA1
PThr2055		phosphorylation
down-regulates
⊣		NUMA123921553SIGNOR-194825
Regulator Mechanism/Effect Target SIGNOR-ID
PLK1phosphorylation
→
down-regulates activity 		NUMA1SIGNOR-279345
CDK1phosphorylation
img/direct_inhibition.png
down-regulates 		NUMA1SIGNOR-194825
TBK1phosphorylation
→
up-regulates activity 		NUMA1SIGNOR-278432