Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
PLK1	SUZ12	Ser546 View in OncoXplorer	SMSEFLEsEDGEVEQ	phosphorylation down-regulates quantity by destabilization	25855382	SIGNOR-275556
PLK1	SUZ12	Ser539 View in OncoXplorer	RPKRTKAsMSEFLES	phosphorylation down-regulates quantity by destabilization	25855382	SIGNOR-275557
PLK1	SUZ12	Ser541 View in OncoXplorer	KRTKASMsEFLESED	phosphorylation down-regulates quantity by destabilization	25855382	SIGNOR-275555
PLK1	SUZ12	–		phosphorylation down-regulates activity	25855382	SIGNOR-278423
CSNK2A2	SUZ12	Ser583 View in OncoXplorer	PQEMEVDsEDEKDPE	phosphorylation up-regulates activity	36351927	SIGNOR-277811
CSNK2A2	SUZ12	Ser583 View in OncoXplorer	PQEMEVDsEDEKDPE	phosphorylation up-regulates activity	36351927	SIGNOR-277797

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
PLK1	phosphorylation up-regulates →	SUZ12 PSer546	phosphorylation down-regulates ⊣	SUZ12	25855382	SIGNOR-275556
PLK1	phosphorylation up-regulates →	SUZ12 PSer539	phosphorylation down-regulates ⊣	SUZ12	25855382	SIGNOR-275557
PLK1	phosphorylation up-regulates →	SUZ12 PSer541	phosphorylation down-regulates ⊣	SUZ12	25855382	SIGNOR-275555
CSNK2A2	phosphorylation up-regulates →	SUZ12 PSer583	phosphorylation up-regulates →	SUZ12	36351927	SIGNOR-277811
CSNK2A2	phosphorylation up-regulates →	SUZ12 PSer583	phosphorylation up-regulates →	SUZ12	36351927	SIGNOR-277797

Regulator	Mechanism/Effect	Target	SIGNOR-ID
PLK1	phosphorylation down-regulates quantity by destabilization	SUZ12	SIGNOR-275556
PLK1	phosphorylation down-regulates quantity by destabilization	SUZ12	SIGNOR-275557
PLK1	phosphorylation down-regulates quantity by destabilization	SUZ12	SIGNOR-275555
PLK1	phosphorylation → down-regulates activity	SUZ12	SIGNOR-278423
CSNK2A2	phosphorylation → up-regulates activity	SUZ12	SIGNOR-277811
CSNK2A2	phosphorylation → up-regulates activity	SUZ12	SIGNOR-277797