| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK1 | SUZ12 | Ser546 | SMSEFLEsEDGEVEQ | phosphorylation down-regulates quantity by destabilization | 25855382 | SIGNOR-275556 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK1 | phosphorylation up-regulates → | SUZ12 PSer546 | phosphorylation down-regulates ⊣ | SUZ12 | 25855382 | SIGNOR-275556 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PLK1 | phosphorylation![]() down-regulates quantity by destabilization | SUZ12 | SIGNOR-275556 |