Entity Details

Name PDCD1
ID Q15116
Role substrate
Enzymatic Domains
Ig-like V-type 35-145
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK1PDCD1Ser261PSGMGTSsPARRGSAphosphorylation
down-regulates quantity by destabilization		36104103SIGNOR-277605
PTPN11PDCD1–dephosphorylation
down-regulates activity		32437509SIGNOR-277052
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
→
PDCD1
PSer261		phosphorylation
down-regulates
⊣		PDCD136104103SIGNOR-277605
Regulator Mechanism/Effect Target SIGNOR-ID
CDK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		PDCD1SIGNOR-277605
PTPN11dephosphorylation
→
down-regulates activity 		PDCD1SIGNOR-277052