Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
AKT1	PEA15	Ser116 View in OncoXplorer	KDIIRQPsEEEIIKL	phosphorylation up-regulates activity	12808093	SIGNOR-102092
PRKCA	PEA15	Ser104 View in OncoXplorer	TKLTRIPsAKKYKDI	phosphorylation down-regulates	15917297	SIGNOR-137841
AKT	PEA15	Ser116 View in OncoXplorer	KDIIRQPsEEEIIKL	phosphorylation up-regulates activity	12808093	SIGNOR-244326
CAMK2G	PEA15	Ser116 View in OncoXplorer	KDIIRQPsEEEIIKL	phosphorylation unknown	9721757	SIGNOR-250701
CAMK2A	PEA15	Ser116 View in OncoXplorer	KDIIRQPsEEEIIKL	phosphorylation up-regulates	15916534	SIGNOR-137614

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
AKT1	phosphorylation up-regulates →	PEA15 PSer116	phosphorylation up-regulates →	PEA15	12808093	SIGNOR-102092
PRKCA	phosphorylation up-regulates →	PEA15 PSer104	phosphorylation down-regulates ⊣	PEA15	15917297	SIGNOR-137841
AKT	phosphorylation up-regulates →	PEA15 PSer116	phosphorylation up-regulates →	PEA15	12808093	SIGNOR-244326
CAMK2G	phosphorylation up-regulates →	PEA15 PSer116	phosphorylation down-regulates ⊣	PEA15	9721757	SIGNOR-250701
CAMK2A	phosphorylation up-regulates →	PEA15 PSer116	phosphorylation up-regulates →	PEA15	15916534	SIGNOR-137614

Regulator	Mechanism/Effect	Target	SIGNOR-ID
AKT1	phosphorylation → up-regulates activity	PEA15	SIGNOR-102092
PRKCA	phosphorylation down-regulates	PEA15	SIGNOR-137841
AKT	phosphorylation → up-regulates activity	PEA15	SIGNOR-244326
CAMK2G	phosphorylation → unknown	PEA15	SIGNOR-250701
CAMK2A	phosphorylation → up-regulates	PEA15	SIGNOR-137614