| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT | PEA15 | Ser116 | KDIIRQPsEEEIIKL | phosphorylation up-regulates activity | 12808093 | SIGNOR-244326 |
| AKT1 | PEA15 | Ser116 | KDIIRQPsEEEIIKL | phosphorylation up-regulates activity | 12808093 | SIGNOR-102092 |
| CAMK2G | PEA15 | Ser116 | KDIIRQPsEEEIIKL | phosphorylation unknown | 9721757 | SIGNOR-250701 |
| CAMK2A | PEA15 | Ser116 | KDIIRQPsEEEIIKL | phosphorylation up-regulates | 15916534 | SIGNOR-137614 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT | phosphorylation up-regulates → | PEA15 PSer116 | phosphorylation up-regulates → | PEA15 | 12808093 | SIGNOR-244326 |
| AKT1 | phosphorylation up-regulates → | PEA15 PSer116 | phosphorylation up-regulates → | PEA15 | 12808093 | SIGNOR-102092 |
| CAMK2G | phosphorylation up-regulates → | PEA15 PSer116 | phosphorylation down-regulates ⊣ | PEA15 | 9721757 | SIGNOR-250701 |
| CAMK2A | phosphorylation up-regulates → | PEA15 PSer116 | phosphorylation up-regulates → | PEA15 | 15916534 | SIGNOR-137614 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT | phosphorylation → up-regulates activity | PEA15 | SIGNOR-244326 |
| AKT1 | phosphorylation → up-regulates activity | PEA15 | SIGNOR-102092 |
| CAMK2G | phosphorylation → unknown | PEA15 | SIGNOR-250701 |
| CAMK2A | phosphorylation → up-regulates | PEA15 | SIGNOR-137614 |
