| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKD1 | PRKD1 | Ser742 | GEKSFRRsVVGTPAY | phosphorylation unknown | 10867018 | SIGNOR-249047 |
| PRKCA | PRKD1 | Ser742 | GEKSFRRsVVGTPAY | phosphorylation up-regulates | 10197446 | SIGNOR-66670 |
| PRKCD | PRKD1 | Ser742 | GEKSFRRsVVGTPAY | phosphorylation up-regulates | 15024053 | SIGNOR-123453 |
| PRKCH | PRKD1 | Ser742 | GEKSFRRsVVGTPAY | phosphorylation up-regulates | 10197446 | SIGNOR-66734 |
| PKA | PRKD1 | Ser742 | GEKSFRRsVVGTPAY | phosphorylation up-regulates activity | 18692497 | SIGNOR-275925 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKD1 | phosphorylation up-regulates → | PRKD1 PSer742 | phosphorylation down-regulates ⊣ | PRKD1 | 10867018 | SIGNOR-249047 |
| PRKCA | phosphorylation up-regulates → | PRKD1 PSer742 | phosphorylation up-regulates → | PRKD1 | 10197446 | SIGNOR-66670 |
| PRKCD | phosphorylation up-regulates → | PRKD1 PSer742 | phosphorylation up-regulates → | PRKD1 | 15024053 | SIGNOR-123453 |
| PRKCH | phosphorylation up-regulates → | PRKD1 PSer742 | phosphorylation up-regulates → | PRKD1 | 10197446 | SIGNOR-66734 |
| PKA | phosphorylation up-regulates → | PRKD1 PSer742 | phosphorylation up-regulates → | PRKD1 | 18692497 | SIGNOR-275925 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKD1 | phosphorylation → unknown | PRKD1 | SIGNOR-249047 |
| PRKCA | phosphorylation → up-regulates | PRKD1 | SIGNOR-66670 |
| PRKCD | phosphorylation → up-regulates | PRKD1 | SIGNOR-123453 |
| PRKCH | phosphorylation → up-regulates | PRKD1 | SIGNOR-66734 |
| PKA | phosphorylation → up-regulates activity | PRKD1 | SIGNOR-275925 |
