| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | PRKD1 | Tyr432 | KEGWMVHyTSKDTLR | phosphorylation up-regulates activity | 12637538 | SIGNOR-247320 |
| ABL1 | PRKD1 | Tyr432 | KEGWMVHyTSKDTLR | phosphorylation unknown | 12637538 | SIGNOR-246211 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | phosphorylation up-regulates → | PRKD1 PTyr432 | phosphorylation up-regulates → | PRKD1 | 12637538 | SIGNOR-247320 |
| ABL1 | phosphorylation up-regulates → | PRKD1 PTyr432 | phosphorylation down-regulates ⊣ | PRKD1 | 12637538 | SIGNOR-246211 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SRC | phosphorylation → up-regulates activity | PRKD1 | SIGNOR-247320 |
| ABL1 | phosphorylation → unknown | PRKD1 | SIGNOR-246211 |
