| Name | STK38 |
| ID | Q15208 |
| Role | kinase |
| Enzymatic Domains |
AGC-kinase C-terminal 383-455 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| STK38 | XPO1 | Ser1055 | EKHKRQMsVPGIFNP | phosphorylation up-regulates activity | 31544310 | SIGNOR-277483 |
| STK38 | MYC | – | phosphorylation down-regulates activity | 23178486 | SIGNOR-280142 | |
| STK38 | CDC25A | Ser76 | SNLQRMGsSESTDSG | phosphorylation down-regulates quantity | 25936524 | SIGNOR-279488 |
| STK38 | CDKN1A | Ser146 | GRKRRQTsMTDFYHS | phosphorylation down-regulates quantity by destabilization | 21262772 | SIGNOR-272961 |
| STK38 | YAP1 | Ser109 | KSHSRQAsTDAGTAG | phosphorylation down-regulates activity | 25601544 | SIGNOR-259856 |
| STK38 | YAP1 | Ser127 | PQHVRAHsSPASLQL | phosphorylation down-regulates activity | 25601544 | SIGNOR-259855 |
| STK38 | STK38 | Ser281 | NRRQLAFsTVGTPDY | phosphorylation up-regulates | 12493777 | SIGNOR-96679 |
| STK38 | STK38 | Thr444 | DWVFINYtYKRFEGL | phosphorylation up-regulates | 12493777 | SIGNOR-96683 |
| STK38 | STK38 | Thr74 | SAHARKEtEFLRLKR | phosphorylation up-regulates | 12493777 | SIGNOR-96687 |
| STK38 | STK38 | Ser281 | NRRQLAFsTVGTPDY | phosphorylation up-regulates | 16314523 | SIGNOR-142514 |
| STK38 | AAK1 | Ser637 | AGHRRILsDVTHSAV | phosphorylation up-regulates activity | 22445341 | SIGNOR-263034 |
| STK38 | RAB3IP | Ser288 | KGHTRNKsTSSAMSG | phosphorylation up-regulates activity | 22445341 | SIGNOR-263036 |
| STK38 | PANX2 | Ser514 | KKHARHFsLDVHPYI | phosphorylation up-regulates activity | 22445341 | SIGNOR-263032 |
| STK38 | RBM24 | – | phosphorylation up-regulates activity | 28322254 | SIGNOR-278291 | |
| STK38 | RAB11FIP5 | Ser307 | FTHKRTYsDEANQMR | phosphorylation up-regulates activity | 22445341 | SIGNOR-263035 |
| STK38 | PI4KB | Ser277 | RTHQRSKsDATASIS | phosphorylation up-regulates activity | 22445341 | SIGNOR-263033 |
| STK38 | HEY1 | Ser68 | RRDRINNsLSELRRL | phosphorylation up-regulates activity | 27129302 | SIGNOR-279489 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| STK38 | phosphorylation up-regulates → | XPO1 PSer1055 | phosphorylation up-regulates → | XPO1 | 31544310 | SIGNOR-277483 |
| STK38 | phosphorylation up-regulates → | CDC25A PSer76 | phosphorylation down-regulates ⊣ | CDC25A | 25936524 | SIGNOR-279488 |
| STK38 | phosphorylation up-regulates → | CDKN1A PSer146 | phosphorylation down-regulates ⊣ | CDKN1A | 21262772 | SIGNOR-272961 |
| STK38 | phosphorylation up-regulates → | YAP1 PSer109 | phosphorylation down-regulates ⊣ | YAP1 | 25601544 | SIGNOR-259856 |
| STK38 | phosphorylation up-regulates → | YAP1 PSer127 | phosphorylation down-regulates ⊣ | YAP1 | 25601544 | SIGNOR-259855 |
| STK38 | phosphorylation up-regulates → | STK38 PSer281 | phosphorylation up-regulates → | STK38 | 12493777 | SIGNOR-96679 |
| STK38 | phosphorylation up-regulates → | STK38 PThr444 | phosphorylation up-regulates → | STK38 | 12493777 | SIGNOR-96683 |
| STK38 | phosphorylation up-regulates → | STK38 PThr74 | phosphorylation up-regulates → | STK38 | 12493777 | SIGNOR-96687 |
| STK38 | phosphorylation up-regulates → | STK38 PSer281 | phosphorylation up-regulates → | STK38 | 16314523 | SIGNOR-142514 |
| STK38 | phosphorylation up-regulates → | AAK1 PSer637 | phosphorylation up-regulates → | AAK1 | 22445341 | SIGNOR-263034 |
| STK38 | phosphorylation up-regulates → | RAB3IP PSer288 | phosphorylation up-regulates → | RAB3IP | 22445341 | SIGNOR-263036 |
| STK38 | phosphorylation up-regulates → | PANX2 PSer514 | phosphorylation up-regulates → | PANX2 | 22445341 | SIGNOR-263032 |
| STK38 | phosphorylation up-regulates → | RAB11FIP5 PSer307 | phosphorylation up-regulates → | RAB11FIP5 | 22445341 | SIGNOR-263035 |
| STK38 | phosphorylation up-regulates → | PI4KB PSer277 | phosphorylation up-regulates → | PI4KB | 22445341 | SIGNOR-263033 |
| STK38 | phosphorylation up-regulates → | HEY1 PSer68 | phosphorylation up-regulates → | HEY1 | 27129302 | SIGNOR-279489 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| STK38 | phosphorylation → up-regulates activity | XPO1 | SIGNOR-277483 |
| STK38 | phosphorylation → down-regulates activity | MYC | SIGNOR-280142 |
| STK38 | phosphorylation → down-regulates quantity | CDC25A | SIGNOR-279488 |
| STK38 | phosphorylation down-regulates quantity by destabilization | CDKN1A | SIGNOR-272961 |
| STK38 | phosphorylation → down-regulates activity | YAP1 | SIGNOR-259856 |
| STK38 | phosphorylation → down-regulates activity | YAP1 | SIGNOR-259855 |
| STK38 | phosphorylation → up-regulates | STK38 | SIGNOR-96679 |
| STK38 | phosphorylation → up-regulates | STK38 | SIGNOR-96683 |
| STK38 | phosphorylation → up-regulates | STK38 | SIGNOR-96687 |
| STK38 | phosphorylation → up-regulates | STK38 | SIGNOR-142514 |
| STK38 | phosphorylation → up-regulates activity | AAK1 | SIGNOR-263034 |
| STK38 | phosphorylation → up-regulates activity | RAB3IP | SIGNOR-263036 |
| STK38 | phosphorylation → up-regulates activity | PANX2 | SIGNOR-263032 |
| STK38 | phosphorylation → up-regulates activity | RBM24 | SIGNOR-278291 |
| STK38 | phosphorylation → up-regulates activity | RAB11FIP5 | SIGNOR-263035 |
| STK38 | phosphorylation → up-regulates activity | PI4KB | SIGNOR-263033 |
| STK38 | phosphorylation → up-regulates activity | HEY1 | SIGNOR-279489 |