| Name | STK38 |
| ID | Q15208 |
| Role | substrate |
| Enzymatic Domains |
AGC-kinase C-terminal 383-455 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAP3K2 | STK38 | Ser91 | LGLEDFEsLKVIGRG | phosphorylation up-regulates quantity by stabilization | 31690749 | SIGNOR-279066 |
| STK38 | STK38 | Thr444 | DWVFINYtYKRFEGL | phosphorylation up-regulates | 12493777 | SIGNOR-96683 |
| PRKACA | STK38 | Ser10 | MTGSTPCsSMSNHTK | phosphorylation down-regulates activity | 22142472 | SIGNOR-276391 |
| GSK3B | STK38 | Thr7 | tPCSSMSN | phosphorylation down-regulates activity | 22142472 | SIGNOR-279464 |
| PLK1 | STK38 | Thr407 | EIKSIDDtSNFDEFP | phosphorylation down-regulates activity | 26057687 | SIGNOR-276915 |
| PRKACA | STK38 | Ser11 | TGSTPCSsMSNHTKE | phosphorylation down-regulates activity | 22142472 | SIGNOR-276390 |
| STK38 | STK38 | Thr74 | SAHARKEtEFLRLKR | phosphorylation up-regulates | 12493777 | SIGNOR-96687 |
| STK4 | STK38 | Thr444 | DWVFINYtYKRFEGL | phosphorylation up-regulates activity | 19062280 | SIGNOR-279641 |
| GSK3B | STK38 | Ser6 | sTPCSSMS | phosphorylation down-regulates activity | 22142472 | SIGNOR-276392 |
| STK24 | STK38 | Thr444 | DWVFINYtYKRFEGL | phosphorylation up-regulates | 16314523 | SIGNOR-142467 |
| PLK1 | STK38 | Thr7 | tPCSSMSN | phosphorylation down-regulates activity | 26057687 | SIGNOR-278420 |
| PLK1 | STK38 | Thr407 | EIKSIDDtSNFDEFP | phosphorylation down-regulates activity | 26057687 | SIGNOR-278421 |
| PLK1 | STK38 | Thr183 | TLLMKKDtLTEEETQ | phosphorylation down-regulates activity | 26057687 | SIGNOR-278422 |
| STK38 | STK38 | Ser281 | NRRQLAFsTVGTPDY | phosphorylation up-regulates | 16314523 | SIGNOR-142514 |
| PLK1 | STK38 | Thr183 | TLLMKKDtLTEEETQ | phosphorylation down-regulates activity | 26057687 | SIGNOR-276913 |
| PLK1 | STK38 | Thr7 | tPCSSMSN | phosphorylation down-regulates activity | 26057687 | SIGNOR-276914 |
| STK38 | STK38 | Ser281 | NRRQLAFsTVGTPDY | phosphorylation up-regulates | 12493777 | SIGNOR-96679 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAP3K2 | phosphorylation up-regulates → | STK38 PSer91 | phosphorylation up-regulates → | STK38 | 31690749 | SIGNOR-279066 |
| STK38 | phosphorylation up-regulates → | STK38 PThr444 | phosphorylation up-regulates → | STK38 | 12493777 | SIGNOR-96683 |
| PRKACA | phosphorylation up-regulates → | STK38 PSer10 | phosphorylation down-regulates ⊣ | STK38 | 22142472 | SIGNOR-276391 |
| GSK3B | phosphorylation up-regulates → | STK38 PThr7 | phosphorylation down-regulates ⊣ | STK38 | 22142472 | SIGNOR-279464 |
| PLK1 | phosphorylation up-regulates → | STK38 PThr407 | phosphorylation down-regulates ⊣ | STK38 | 26057687 | SIGNOR-276915 |
| PRKACA | phosphorylation up-regulates → | STK38 PSer11 | phosphorylation down-regulates ⊣ | STK38 | 22142472 | SIGNOR-276390 |
| STK38 | phosphorylation up-regulates → | STK38 PThr74 | phosphorylation up-regulates → | STK38 | 12493777 | SIGNOR-96687 |
| STK4 | phosphorylation up-regulates → | STK38 PThr444 | phosphorylation up-regulates → | STK38 | 19062280 | SIGNOR-279641 |
| GSK3B | phosphorylation up-regulates → | STK38 PSer6 | phosphorylation down-regulates ⊣ | STK38 | 22142472 | SIGNOR-276392 |
| STK24 | phosphorylation up-regulates → | STK38 PThr444 | phosphorylation up-regulates → | STK38 | 16314523 | SIGNOR-142467 |
| PLK1 | phosphorylation up-regulates → | STK38 PThr7 | phosphorylation down-regulates ⊣ | STK38 | 26057687 | SIGNOR-278420 |
| PLK1 | phosphorylation up-regulates → | STK38 PThr407 | phosphorylation down-regulates ⊣ | STK38 | 26057687 | SIGNOR-278421 |
| PLK1 | phosphorylation up-regulates → | STK38 PThr183 | phosphorylation down-regulates ⊣ | STK38 | 26057687 | SIGNOR-278422 |
| STK38 | phosphorylation up-regulates → | STK38 PSer281 | phosphorylation up-regulates → | STK38 | 16314523 | SIGNOR-142514 |
| PLK1 | phosphorylation up-regulates → | STK38 PThr183 | phosphorylation down-regulates ⊣ | STK38 | 26057687 | SIGNOR-276913 |
| PLK1 | phosphorylation up-regulates → | STK38 PThr7 | phosphorylation down-regulates ⊣ | STK38 | 26057687 | SIGNOR-276914 |
| STK38 | phosphorylation up-regulates → | STK38 PSer281 | phosphorylation up-regulates → | STK38 | 12493777 | SIGNOR-96679 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAP3K2 | phosphorylation → up-regulates quantity by stabilization | STK38 | SIGNOR-279066 |
| STK38 | phosphorylation → up-regulates | STK38 | SIGNOR-96683 |
| PRKACA | phosphorylation → down-regulates activity | STK38 | SIGNOR-276391 |
| GSK3B | phosphorylation → down-regulates activity | STK38 | SIGNOR-279464 |
| PLK1 | phosphorylation → down-regulates activity | STK38 | SIGNOR-276915 |
| PRKACA | phosphorylation → down-regulates activity | STK38 | SIGNOR-276390 |
| STK38 | phosphorylation → up-regulates | STK38 | SIGNOR-96687 |
| STK4 | phosphorylation → up-regulates activity | STK38 | SIGNOR-279641 |
| GSK3B | phosphorylation → down-regulates activity | STK38 | SIGNOR-276392 |
| STK24 | phosphorylation → up-regulates | STK38 | SIGNOR-142467 |
| PLK1 | phosphorylation → down-regulates activity | STK38 | SIGNOR-278420 |
| PLK1 | phosphorylation → down-regulates activity | STK38 | SIGNOR-278421 |
| PLK1 | phosphorylation → down-regulates activity | STK38 | SIGNOR-278422 |
| STK38 | phosphorylation → up-regulates | STK38 | SIGNOR-142514 |
| PLK1 | phosphorylation → down-regulates activity | STK38 | SIGNOR-276913 |
| PLK1 | phosphorylation → down-regulates activity | STK38 | SIGNOR-276914 |
| STK38 | phosphorylation → up-regulates | STK38 | SIGNOR-96679 |