Entity Details

Name PTPA
ID Q15257
Role phosphatase
Enzymatic Domains
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PTPAAKT1Ser473RPHFPQFsYSASGTAdephosphorylation
down-regulates		21159657SIGNOR-252607
PTPAAKTSer473RPHFPQFsYSASGTAdephosphorylation
down-regulates		21159657SIGNOR-170699
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PTPAdephosphorylation
down-regulates
⊣
AKT1
PSer473		dephosphorylation
up-regulates
→		AKT121159657SIGNOR-252607
PTPAdephosphorylation
down-regulates
⊣
AKT
PSer473		dephosphorylation
up-regulates
→		AKT21159657SIGNOR-170699
Regulator Mechanism/Effect Target SIGNOR-ID
PTPAdephosphorylation
img/direct_inhibition.png
down-regulates 		AKT1SIGNOR-252607
PTPAdephosphorylation
img/direct_inhibition.png
down-regulates 		AKTSIGNOR-170699