Entity Details

Name RET/PTC2
ID Q15300
Role kinase
Enzymatic Domains
Cyclic nucleotide-binding 137-236

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PROSITE
Protein kinase 248-540

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PROSITE
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
RET/PTC2STAT3Tyr705DPGSAAPyLKTKFICphosphorylation
up-regulates activity		12637586SIGNOR-260917
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
RET/PTC2phosphorylation
up-regulates
→
STAT3
PTyr705		phosphorylation
up-regulates
→		STAT312637586SIGNOR-260917
Regulator Mechanism/Effect Target SIGNOR-ID
RET/PTC2phosphorylation
→
up-regulates activity 		STAT3SIGNOR-260917