Entity Details

Name ERBB4
ID Q15303
Role substrate
Enzymatic Domains
Protein kinase 718-985
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK3ERBB4Thr699
View in OncoXplorer
TELVEPLtPSGTAPNphosphorylation
down-regulates activity		31053301SIGNOR-277448
MAPK3ERBB4Ser1051NRSEIGHsPPPAYTPphosphorylation
down-regulates activity		31053301SIGNOR-277449
CDK5ERBB4Thr1152LDEEGYMtPMRDKPKphosphorylation
up-regulates activity		24142862SIGNOR-278436
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK3phosphorylation
up-regulates
→
ERBB4
PThr699		phosphorylation
down-regulates
⊣		ERBB431053301SIGNOR-277448
MAPK3phosphorylation
up-regulates
→
ERBB4
PSer1051		phosphorylation
down-regulates
⊣		ERBB431053301SIGNOR-277449
CDK5phosphorylation
up-regulates
→
ERBB4
PThr1152		phosphorylation
up-regulates
→		ERBB424142862SIGNOR-278436
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK3phosphorylation
→
down-regulates activity 		ERBB4SIGNOR-277448
MAPK3phosphorylation
→
down-regulates activity 		ERBB4SIGNOR-277449
CDK5phosphorylation
→
up-regulates activity 		ERBB4SIGNOR-278436