| Name | RPS6KA2 |
| ID | Q15349 |
| Role | substrate |
| Enzymatic Domains |
Protein kinase 1 59-318 PROSITE-ProRule
AGC-kinase C-terminal 319-388 PROSITE-ProRule
Protein kinase 2 415-672 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MTOR | RPS6KA2 | – | phosphorylation up-regulates activity | 20602111 | SIGNOR-279232 | |
| MAPK1 | RPS6KA2 | – | phosphorylation up-regulates | 19282669 | SIGNOR-161515 | |
| Gbeta | RPS6KA2 | – | phosphorylation up-regulates | 8939914 | SIGNOR-270018 | |
| MAPK3 | RPS6KA2 | – | phosphorylation up-regulates | 8939914 | SIGNOR-44949 | |
| ERK1/2 | RPS6KA2 | – | phosphorylation up-regulates | 8939914 | SIGNOR-270144 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MTOR | phosphorylation → up-regulates activity | RPS6KA2 | SIGNOR-279232 |
| MAPK1 | phosphorylation → up-regulates | RPS6KA2 | SIGNOR-161515 |
| Gbeta | phosphorylation → up-regulates | RPS6KA2 | SIGNOR-270018 |
| MAPK3 | phosphorylation → up-regulates | RPS6KA2 | SIGNOR-44949 |
| ERK1/2 | phosphorylation → up-regulates | RPS6KA2 | SIGNOR-270144 |