Entity Details

Name TESK1
ID Q15569
Role kinase
Enzymatic Domains
Protein kinase 57-314
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
TESK1CFL1Ser3sGVAVSDGphosphorylation
down-regulates activity		11294912SIGNOR-106777
TESK1CFL1Ser3sGVAVSDGphosphorylation
down-regulates activity		11418599SIGNOR-246723
TESK1TESK1Ser220EPLAVVGsPYWMAPEphosphorylation
up-regulates activity		10207045SIGNOR-246667
TESK1TESK1Ser220EPLAVVGsPYWMAPEphosphorylation
up-regulates activity		10207045SIGNOR-260825
TESK1CFL2Ser3sGVTVNDEphosphorylation
down-regulates activity		11418599SIGNOR-246719
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
TESK1phosphorylation
up-regulates
→
CFL1
PSer3		phosphorylation
down-regulates
⊣		CFL111294912SIGNOR-106777
TESK1phosphorylation
up-regulates
→
CFL1
PSer3		phosphorylation
down-regulates
⊣		CFL111418599SIGNOR-246723
TESK1phosphorylation
up-regulates
→
TESK1
PSer220		phosphorylation
up-regulates
→		TESK110207045SIGNOR-246667
TESK1phosphorylation
up-regulates
→
TESK1
PSer220		phosphorylation
up-regulates
→		TESK110207045SIGNOR-260825
TESK1phosphorylation
up-regulates
→
CFL2
PSer3		phosphorylation
down-regulates
⊣		CFL211418599SIGNOR-246719
Regulator Mechanism/Effect Target SIGNOR-ID
TESK1phosphorylation
→
down-regulates activity 		CFL1SIGNOR-106777
TESK1phosphorylation
→
down-regulates activity 		CFL1SIGNOR-246723
TESK1phosphorylation
→
up-regulates activity 		TESK1SIGNOR-246667
TESK1phosphorylation
→
up-regulates activity 		TESK1SIGNOR-260825
TESK1phosphorylation
→
down-regulates activity 		CFL2SIGNOR-246719