| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KB1 | TARBP2 | Ser286 | LRSCSLGsLGALGPA | phosphorylation up-regulates activity | 27407113 | SIGNOR-274068 |
| RPS6KB2 | TARBP2 | Ser286 | LRSCSLGsLGALGPA | phosphorylation up-regulates activity | 27407113 | SIGNOR-274069 |
| AKT1 | TARBP2 | Ser286 | LRSCSLGsLGALGPA | phosphorylation up-regulates activity | 27407113 | SIGNOR-274067 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KB1 | phosphorylation up-regulates → | TARBP2 PSer286 | phosphorylation up-regulates → | TARBP2 | 27407113 | SIGNOR-274068 |
| RPS6KB2 | phosphorylation up-regulates → | TARBP2 PSer286 | phosphorylation up-regulates → | TARBP2 | 27407113 | SIGNOR-274069 |
| AKT1 | phosphorylation up-regulates → | TARBP2 PSer286 | phosphorylation up-regulates → | TARBP2 | 27407113 | SIGNOR-274067 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| RPS6KB1 | phosphorylation → up-regulates activity | TARBP2 | SIGNOR-274068 |
| RPS6KB2 | phosphorylation → up-regulates activity | TARBP2 | SIGNOR-274069 |
| AKT1 | phosphorylation → up-regulates activity | TARBP2 | SIGNOR-274067 |