| Name | SPEG |
| ID | Q15772 |
| Role | kinase |
| Enzymatic Domains |
Ig-like 1 43-124
Ig-like 2 722-810
Ig-like 3 869-958
Ig-like 4 963-1057
Ig-like 5 1064-1152
Ig-like 6 1188-1278
Fibronectin type-III 1 1285-1382 PROSITE-ProRule
Ig-like 7 1384-1480
Ig-like 8 1485-1573
Protein kinase 1 1601-1854 PROSITE-ProRule
Ig-like 9 2583-2673
Fibronectin type-III 2 2680-2774 PROSITE-ProRule
Protein kinase 2 2966-3218 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SPEG | RYR2 | – | phosphorylation down-regulates activity | 32683896 | SIGNOR-279114 | |
| SPEG | JPH2 | – | phosphorylation up-regulates activity | 27729468 | SIGNOR-279759 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SPEG | phosphorylation → down-regulates activity | RYR2 | SIGNOR-279114 |
| SPEG | phosphorylation → up-regulates activity | JPH2 | SIGNOR-279759 |