Entity Details

Name MAP4K4_Thr322
ID Q15797
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MINK1SMAD1Thr322SNVNRNStIENTRRHphosphorylation
down-regulates activity		21690388SIGNOR-276336
MAP4K4SMAD1Thr322SNVNRNStIENTRRHphosphorylation
down-regulates activity		21690388SIGNOR-276335
TNIKSMAD1Thr322SNVNRNStIENTRRHphosphorylation
down-regulates activity		21690388SIGNOR-276334
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MINK1phosphorylation
up-regulates
→
SMAD1
PThr322		phosphorylation
down-regulates
⊣		SMAD121690388SIGNOR-276336
MAP4K4phosphorylation
up-regulates
→
SMAD1
PThr322		phosphorylation
down-regulates
⊣		SMAD121690388SIGNOR-276335
TNIKphosphorylation
up-regulates
→
SMAD1
PThr322		phosphorylation
down-regulates
⊣		SMAD121690388SIGNOR-276334
Regulator Mechanism/Effect Target SIGNOR-ID
MINK1phosphorylation
→
down-regulates activity 		SMAD1SIGNOR-276336
MAP4K4phosphorylation
→
down-regulates activity 		SMAD1SIGNOR-276335
TNIKphosphorylation
→
down-regulates activity 		SMAD1SIGNOR-276334