Entity Details

Name GRK1_Ser21
ID Q15835
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GRK1GRK1Ser21AFIAARGsFDGSSSQphosphorylation
down-regulates activity		1527025SIGNOR-251186
PKAGRK1Ser21AFIAARGsFDGSSSQphosphorylation
down-regulates activity		15946941SIGNOR-274079
PKAGRK1Ser21AFIAARGsFDGSSSQphosphorylation
down-regulates activity		15946941SIGNOR-276034
PKAGRK1Ser21AFIAARGsFDGSSSQphosphorylation
down-regulates activity		15946941SIGNOR-260841
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GRK1phosphorylation
up-regulates
→
GRK1
PSer21		phosphorylation
down-regulates
⊣		GRK11527025SIGNOR-251186
PKAphosphorylation
up-regulates
→
GRK1
PSer21		phosphorylation
down-regulates
⊣		GRK115946941SIGNOR-274079
PKAphosphorylation
up-regulates
→
GRK1
PSer21		phosphorylation
down-regulates
⊣		GRK115946941SIGNOR-276034
PKAphosphorylation
up-regulates
→
GRK1
PSer21		phosphorylation
down-regulates
⊣		GRK115946941SIGNOR-260841
Regulator Mechanism/Effect Target SIGNOR-ID
GRK1phosphorylation
→
down-regulates activity 		GRK1SIGNOR-251186
PKAphosphorylation
→
down-regulates activity 		GRK1SIGNOR-274079
PKAphosphorylation
→
down-regulates activity 		GRK1SIGNOR-276034
PKAphosphorylation
→
down-regulates activity 		GRK1SIGNOR-260841