Entity Details

Name GRK5_Ser118
ID Q16143
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GRK5SNCBSer118LMEPEGEsYEDPPQEphosphorylation
down-regulates activity		10852916SIGNOR-251203
PLK2SNCBSer118LMEPEGEsYEDPPQEphosphorylation
down-regulates activity		19889641SIGNOR-189049
PLK3SNCBSer118LMEPEGEsYEDPPQEphosphorylation
down-regulates activity		19889641SIGNOR-189057
PLK1SNCBSer118LMEPEGEsYEDPPQEphosphorylation
down-regulates activity		19889641SIGNOR-176079
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GRK5phosphorylation
up-regulates
→
SNCB
PSer118		phosphorylation
down-regulates
⊣		SNCB10852916SIGNOR-251203
PLK2phosphorylation
up-regulates
→
SNCB
PSer118		phosphorylation
down-regulates
⊣		SNCB19889641SIGNOR-189049
PLK3phosphorylation
up-regulates
→
SNCB
PSer118		phosphorylation
down-regulates
⊣		SNCB19889641SIGNOR-189057
PLK1phosphorylation
up-regulates
→
SNCB
PSer118		phosphorylation
down-regulates
⊣		SNCB19889641SIGNOR-176079
Regulator Mechanism/Effect Target SIGNOR-ID
GRK5phosphorylation
→
down-regulates activity 		SNCBSIGNOR-251203
PLK2phosphorylation
→
down-regulates activity 		SNCBSIGNOR-189049
PLK3phosphorylation
→
down-regulates activity 		SNCBSIGNOR-189057
PLK1phosphorylation
→
down-regulates activity 		SNCBSIGNOR-176079