Entity Details

Name	CCDC6
ID	Q16204
Role	substrate
Enzymatic Domains
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Data Summary

PTM Format

SIGNOR Summary

Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
ATM	CCDC6	Thr434	TPPPSPNtQTPVQPP	phosphorylation up-regulates	23108047	SIGNOR-199276
CDK2	CCDC6	Ser244 View in OncoXplorer	QPVSAPPsPRDISME	phosphorylation up-regulates	14712216	SIGNOR-121198
MAPK3	CCDC6	Ser244 View in OncoXplorer	QPVSAPPsPRDISME	phosphorylation up-regulates activity	14712216	SIGNOR-276003

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
ATM	phosphorylation up-regulates →	CCDC6 PThr434	phosphorylation up-regulates →	CCDC6	23108047	SIGNOR-199276
CDK2	phosphorylation up-regulates →	CCDC6 PSer244	phosphorylation up-regulates →	CCDC6	14712216	SIGNOR-121198
MAPK3	phosphorylation up-regulates →	CCDC6 PSer244	phosphorylation up-regulates →	CCDC6	14712216	SIGNOR-276003

Regulator	Mechanism/Effect	Target	SIGNOR-ID
ATM	phosphorylation → up-regulates	CCDC6	SIGNOR-199276
CDK2	phosphorylation → up-regulates	CCDC6	SIGNOR-121198
MAPK3	phosphorylation → up-regulates activity	CCDC6	SIGNOR-276003