| Name | PKN2 |
| ID | Q16513 |
| Role | kinase |
| Enzymatic Domains |
REM-1 1 33-109 PROSITE-ProRule
REM-1 2 121-203 PROSITE-ProRule
REM-1 3 204-284 PROSITE-ProRule
C2 353-473 PROSITE-ProRule
Protein kinase 657-916 PROSITE-ProRule
AGC-kinase C-terminal 917-984 PROSITE-ProRule |
View in  |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PKN2 | MEFV | Ser208 | VRLRRNAsSAGRLQG | phosphorylation down-regulates activity | 27270401 | SIGNOR-275464 |
| PKN2 | MEFV | Ser242 | SGKMRPRsLEVTIST | phosphorylation down-regulates activity | 27270401 | SIGNOR-275463 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PKN2 | phosphorylation up-regulates → | MEFV PSer208 | phosphorylation down-regulates ⊣ | MEFV | 27270401 | SIGNOR-275464 |
| PKN2 | phosphorylation up-regulates → | MEFV PSer242 | phosphorylation down-regulates ⊣ | MEFV | 27270401 | SIGNOR-275463 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PKN2 | phosphorylation → down-regulates activity | MEFV | SIGNOR-275464 |
| PKN2 | phosphorylation → down-regulates activity | MEFV | SIGNOR-275463 |