| Name | PKN2 |
| ID | Q16513 |
| Role | substrate |
| Enzymatic Domains |
REM-1 1 33-109 PROSITE-ProRule
REM-1 2 121-203 PROSITE-ProRule
REM-1 3 204-284 PROSITE-ProRule
C2 353-473 PROSITE-ProRule
Protein kinase 657-916 PROSITE-ProRule
AGC-kinase C-terminal 917-984 PROSITE-ProRule |
View in  |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PDPK1 | PKN2 | Thr816 | GYGDRTStFCGTPEF | phosphorylation up-regulates | 10753910 | SIGNOR-76710 |
| PDK1 | PKN2 | Thr816 | GYGDRTStFCGTPEF | phosphorylation up-regulates activity | 10753910 | SIGNOR-250265 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PDPK1 | phosphorylation up-regulates → | PKN2 PThr816 | phosphorylation up-regulates → | PKN2 | 10753910 | SIGNOR-76710 |
| PDK1 | phosphorylation up-regulates → | PKN2 PThr816 | phosphorylation up-regulates → | PKN2 | 10753910 | SIGNOR-250265 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PDPK1 | phosphorylation → up-regulates | PKN2 | SIGNOR-76710 |
| PDK1 | phosphorylation → up-regulates activity | PKN2 | SIGNOR-250265 |