| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP5C | CDC37 | Ser13 | VWDHIEVsDDEDETH | dephosphorylation down-regulates activity | 18922470 | SIGNOR-248539 |
| CSNK2A1 | CDC37 | Ser13 | VWDHIEVsDDEDETH | phosphorylation up-regulates activity | 12930845 | SIGNOR-250838 |
| CSNK2A2 | CDC37 | Ser13 | VWDHIEVsDDEDETH | phosphorylation up-regulates activity | 12930845 | SIGNOR-250982 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP5C | dephosphorylation down-regulates ⊣ | CDC37 PSer13 | dephosphorylation up-regulates → | CDC37 | 18922470 | SIGNOR-248539 |
| CSNK2A1 | phosphorylation up-regulates → | CDC37 PSer13 | phosphorylation up-regulates → | CDC37 | 12930845 | SIGNOR-250838 |
| CSNK2A2 | phosphorylation up-regulates → | CDC37 PSer13 | phosphorylation up-regulates → | CDC37 | 12930845 | SIGNOR-250982 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP5C | dephosphorylation → down-regulates activity | CDC37 | SIGNOR-248539 |
| CSNK2A1 | phosphorylation → up-regulates activity | CDC37 | SIGNOR-250838 |
| CSNK2A2 | phosphorylation → up-regulates activity | CDC37 | SIGNOR-250982 |