| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | DPYSL2 | Thr514 | SVTPKTVtPASSAKT | phosphorylation down-regulates activity | 15652488 | SIGNOR-133255 |
| GSK3B | DPYSL2 | Thr514 | SVTPKTVtPASSAKT | phosphorylation down-regulates activity | 25040932 | SIGNOR-264840 |
| TTBK1 | DPYSL2 | Thr514 | SVTPKTVtPASSAKT | phosphorylation up-regulates activity | 32019603 | SIGNOR-279313 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | phosphorylation up-regulates → | DPYSL2 PThr514 | phosphorylation down-regulates ⊣ | DPYSL2 | 15652488 | SIGNOR-133255 |
| GSK3B | phosphorylation up-regulates → | DPYSL2 PThr514 | phosphorylation down-regulates ⊣ | DPYSL2 | 25040932 | SIGNOR-264840 |
| TTBK1 | phosphorylation up-regulates → | DPYSL2 PThr514 | phosphorylation up-regulates → | DPYSL2 | 32019603 | SIGNOR-279313 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3B | phosphorylation → down-regulates activity | DPYSL2 | SIGNOR-133255 |
| GSK3B | phosphorylation → down-regulates activity | DPYSL2 | SIGNOR-264840 |
| TTBK1 | phosphorylation → up-regulates activity | DPYSL2 | SIGNOR-279313 |