| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ROCK1 | DPYSL2 | Thr555 | DNIPRRTtQRIVAPP | phosphorylation unknown | 10818093 | SIGNOR-249042 |
| ROCK2 | DPYSL2 | Thr555 | DNIPRRTtQRIVAPP | phosphorylation up-regulates | 10818093 | SIGNOR-77543 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ROCK1 | phosphorylation up-regulates → | DPYSL2 PThr555 | phosphorylation down-regulates ⊣ | DPYSL2 | 10818093 | SIGNOR-249042 |
| ROCK2 | phosphorylation up-regulates → | DPYSL2 PThr555 | phosphorylation up-regulates → | DPYSL2 | 10818093 | SIGNOR-77543 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ROCK1 | phosphorylation → unknown | DPYSL2 | SIGNOR-249042 |
| ROCK2 | phosphorylation → up-regulates | DPYSL2 | SIGNOR-77543 |
