| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCZ | NREP | Ser59 | LGSSELRsPRISYLH | phosphorylation down-regulates quantity by destabilization | 16229809 | SIGNOR-273831 |
| PRKCE | NREP | Ser59 | LGSSELRsPRISYLH | phosphorylation down-regulates quantity by destabilization | 16229809 | SIGNOR-273830 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCZ | phosphorylation up-regulates → | NREP PSer59 | phosphorylation down-regulates ⊣ | NREP | 16229809 | SIGNOR-273831 |
| PRKCE | phosphorylation up-regulates → | NREP PSer59 | phosphorylation down-regulates ⊣ | NREP | 16229809 | SIGNOR-273830 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCZ | phosphorylation![]() down-regulates quantity by destabilization | NREP | SIGNOR-273831 |
| PRKCE | phosphorylation![]() down-regulates quantity by destabilization | NREP | SIGNOR-273830 |