Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
MAPKAPK3	EEF2K	Ser377	PPLLRPLsENSGDEN	phosphorylation unknown	12171600	SIGNOR-249709
MAPKAPK3	HSPB1	Ser15	FSLLRGPsWDPFRDW	phosphorylation unknown	8774846	SIGNOR-250159
MAPKAPK3	HSPB1	Ser78	PAYSRALsRQLSSGV	phosphorylation unknown	8774846	SIGNOR-250160
MAPKAPK3	HSPB1	Ser82	RALSRQLsSGVSEIR	phosphorylation unknown	8774846	SIGNOR-250161
MAPKAPK3	BECN1	Ser90	IPPARMMsTESANSF	phosphorylation up-regulates activity	25693418	SIGNOR-279342
MAPKAPK3	RCSD1	Ser179	RRFRRSQsDCGELGD	phosphorylation down-regulates activity	15850461	SIGNOR-263081
MAPKAPK3	RCSD1	Ser244	PPLRRSPsRTEKQEE	phosphorylation down-regulates activity	15850461	SIGNOR-263082

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
MAPKAPK3	phosphorylation up-regulates →	EEF2K PSer377	phosphorylation down-regulates ⊣	EEF2K	12171600	SIGNOR-249709
MAPKAPK3	phosphorylation up-regulates →	HSPB1 PSer15	phosphorylation down-regulates ⊣	HSPB1	8774846	SIGNOR-250159
MAPKAPK3	phosphorylation up-regulates →	HSPB1 PSer78	phosphorylation down-regulates ⊣	HSPB1	8774846	SIGNOR-250160
MAPKAPK3	phosphorylation up-regulates →	HSPB1 PSer82	phosphorylation down-regulates ⊣	HSPB1	8774846	SIGNOR-250161
MAPKAPK3	phosphorylation up-regulates →	BECN1 PSer90	phosphorylation up-regulates →	BECN1	25693418	SIGNOR-279342
MAPKAPK3	phosphorylation up-regulates →	RCSD1 PSer179	phosphorylation down-regulates ⊣	RCSD1	15850461	SIGNOR-263081
MAPKAPK3	phosphorylation up-regulates →	RCSD1 PSer244	phosphorylation down-regulates ⊣	RCSD1	15850461	SIGNOR-263082

Regulator	Mechanism/Effect	Target	SIGNOR-ID
MAPKAPK3	phosphorylation → unknown	EEF2K	SIGNOR-249709
MAPKAPK3	phosphorylation → unknown	HSPB1	SIGNOR-250159
MAPKAPK3	phosphorylation → unknown	HSPB1	SIGNOR-250160
MAPKAPK3	phosphorylation → unknown	HSPB1	SIGNOR-250161
MAPKAPK3	phosphorylation → up-regulates activity	BECN1	SIGNOR-279342
MAPKAPK3	phosphorylation → down-regulates activity	RCSD1	SIGNOR-263081
MAPKAPK3	phosphorylation → down-regulates activity	RCSD1	SIGNOR-263082