Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
PHKG1	PYGL	Ser15	QEKRRQIsIRGIVGV	phosphorylation up-regulates activity	22225877	SIGNOR-267399
PHKG1	MAPT	Ser554	RTPPKSPsSAKSRLQ	phosphorylation down-regulates activity	8999860	SIGNOR-250283
PHKG1	MAPT	Ser579	NVKSKIGsTENLKHQ	phosphorylation down-regulates activity	8999860	SIGNOR-250284
PHKG1	MAPT	Ser602	INKKLDLsNVQSKCG	phosphorylation down-regulates activity	8999860	SIGNOR-250285
PHKG1	MAPT	Ser622	KHVPGGGsVQIVYKP	phosphorylation down-regulates activity	8999860	SIGNOR-250286
PHKG1	MAPT	Ser669	DFKDRVQsKIGSLDN	phosphorylation down-regulates activity	8999860	SIGNOR-250287
PHKG1	PYGM	Ser15	QEKRKQIsVRGLAGV	phosphorylation up-regulates activity	22225877	SIGNOR-267398
PHKG1	PHKG1	Ser31	EILGRGVsSVVRRCI	phosphorylation unknown	7935360	SIGNOR-250388
PHKG1	PHKG1	Ser82	VDILRKVsGHPNIIQ	phosphorylation unknown	7935360	SIGNOR-250389
PHKG1	PYG	–		phosphorylation up-regulates activity	22225877	SIGNOR-267960

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
PHKG1	phosphorylation up-regulates →	PYGL PSer15	phosphorylation up-regulates →	PYGL	22225877	SIGNOR-267399
PHKG1	phosphorylation up-regulates →	MAPT PSer554	phosphorylation down-regulates ⊣	MAPT	8999860	SIGNOR-250283
PHKG1	phosphorylation up-regulates →	MAPT PSer579	phosphorylation down-regulates ⊣	MAPT	8999860	SIGNOR-250284
PHKG1	phosphorylation up-regulates →	MAPT PSer602	phosphorylation down-regulates ⊣	MAPT	8999860	SIGNOR-250285
PHKG1	phosphorylation up-regulates →	MAPT PSer622	phosphorylation down-regulates ⊣	MAPT	8999860	SIGNOR-250286
PHKG1	phosphorylation up-regulates →	MAPT PSer669	phosphorylation down-regulates ⊣	MAPT	8999860	SIGNOR-250287
PHKG1	phosphorylation up-regulates →	PYGM PSer15	phosphorylation up-regulates →	PYGM	22225877	SIGNOR-267398
PHKG1	phosphorylation up-regulates →	PHKG1 PSer31	phosphorylation down-regulates ⊣	PHKG1	7935360	SIGNOR-250388
PHKG1	phosphorylation up-regulates →	PHKG1 PSer82	phosphorylation down-regulates ⊣	PHKG1	7935360	SIGNOR-250389

Regulator	Mechanism/Effect	Target	SIGNOR-ID
PHKG1	phosphorylation → up-regulates activity	PYGL	SIGNOR-267399
PHKG1	phosphorylation → down-regulates activity	MAPT	SIGNOR-250283
PHKG1	phosphorylation → down-regulates activity	MAPT	SIGNOR-250284
PHKG1	phosphorylation → down-regulates activity	MAPT	SIGNOR-250285
PHKG1	phosphorylation → down-regulates activity	MAPT	SIGNOR-250286
PHKG1	phosphorylation → down-regulates activity	MAPT	SIGNOR-250287
PHKG1	phosphorylation → up-regulates activity	PYGM	SIGNOR-267398
PHKG1	phosphorylation → unknown	PHKG1	SIGNOR-250388
PHKG1	phosphorylation → unknown	PHKG1	SIGNOR-250389
PHKG1	phosphorylation → up-regulates activity	PYG	SIGNOR-267960