| Name | PTPN21 |
| ID | Q16825 |
| Role | phosphatase |
| Enzymatic Domains |
FERM 23-308 PROSITE-ProRule
Tyrosine-protein phosphatase 896-1167 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN21 | SRC | Tyr530 | FTSTEPQyQPGENL | dephosphorylation up-regulates | 15143158 | SIGNOR-124774 |
| PTPN21 | SRC | Tyr530 | FTSTEPQyQPGENL | dephosphorylation up-regulates activity | 15143158 | SIGNOR-248725 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN21 | dephosphorylation down-regulates ⊣ | SRC PTyr530 | dephosphorylation down-regulates ⊣ | SRC | 15143158 | SIGNOR-124774 |
| PTPN21 | dephosphorylation down-regulates ⊣ | SRC PTyr530 | dephosphorylation down-regulates ⊣ | SRC | 15143158 | SIGNOR-248725 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTPN21 | dephosphorylation → up-regulates | SRC | SIGNOR-124774 |
| PTPN21 | dephosphorylation → up-regulates activity | SRC | SIGNOR-248725 |