Entity Details

Name AKT_Ser461
ID Q16875
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKT1PFKFB3Ser461NPLMRRNsVTPLASPphosphorylation
up-regulates		15896703SIGNOR-252477
AKTPFKFB3Ser461NPLMRRNsVTPLASPphosphorylation
up-regulates		15896703SIGNOR-137241
PRKAA1PFKFB3Ser461NPLMRRNsVTPLASPphosphorylation
up-regulates		12065600SIGNOR-89760
AMPKPFKFB3Ser461NPLMRRNsVTPLASPphosphorylation
up-regulates		12065600SIGNOR-216639
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKT1phosphorylation
up-regulates
→
PFKFB3
PSer461		phosphorylation
up-regulates
→		PFKFB315896703SIGNOR-252477
AKTphosphorylation
up-regulates
→
PFKFB3
PSer461		phosphorylation
up-regulates
→		PFKFB315896703SIGNOR-137241
PRKAA1phosphorylation
up-regulates
→
PFKFB3
PSer461		phosphorylation
up-regulates
→		PFKFB312065600SIGNOR-89760
AMPKphosphorylation
up-regulates
→
PFKFB3
PSer461		phosphorylation
up-regulates
→		PFKFB312065600SIGNOR-216639
Regulator Mechanism/Effect Target SIGNOR-ID
AKT1phosphorylation
→
up-regulates 		PFKFB3SIGNOR-252477
AKTphosphorylation
→
up-regulates 		PFKFB3SIGNOR-137241
PRKAA1phosphorylation
→
up-regulates 		PFKFB3SIGNOR-89760
AMPKphosphorylation
→
up-regulates 		PFKFB3SIGNOR-216639