| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| IKBKB | PFKFB3 | Ser269 | QGRIGGDsGLSSRGK | phosphorylation down-regulates activity | 27585591 | SIGNOR-277278 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| IKBKB | phosphorylation up-regulates → | PFKFB3 PSer269 | phosphorylation down-regulates ⊣ | PFKFB3 | 27585591 | SIGNOR-277278 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| IKBKB | phosphorylation → down-regulates activity | PFKFB3 | SIGNOR-277278 |