Entity Details

Name AKT_Ser457
ID Q53EL6
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKTPDCD4Ser457RGRKRFVsEGDGGRLphosphorylation
down-regulates		16357133SIGNOR-143098
AKT1PDCD4Ser457RGRKRFVsEGDGGRLphosphorylation
down-regulates		16357133SIGNOR-252488
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKTphosphorylation
up-regulates
→
PDCD4
PSer457		phosphorylation
down-regulates
⊣		PDCD416357133SIGNOR-143098
AKT1phosphorylation
up-regulates
→
PDCD4
PSer457		phosphorylation
down-regulates
⊣		PDCD416357133SIGNOR-252488
Regulator Mechanism/Effect Target SIGNOR-ID
AKTphosphorylation
img/direct_inhibition.png
down-regulates 		PDCD4SIGNOR-143098
AKT1phosphorylation
img/direct_inhibition.png
down-regulates 		PDCD4SIGNOR-252488