Entity Details

Name SIK3_Ser70
ID Q53ET0
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SIK1CRTC2Ser70RSSHYGGsLPNVNQIphosphorylation
down-regulates activity		16306228SIGNOR-249169
SIK3CRTC2Ser70RSSHYGGsLPNVNQIphosphorylation
down-regulates activity		16306228SIGNOR-249171
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SIK1phosphorylation
up-regulates
→
CRTC2
PSer70		phosphorylation
down-regulates
⊣		CRTC216306228SIGNOR-249169
SIK3phosphorylation
up-regulates
→
CRTC2
PSer70		phosphorylation
down-regulates
⊣		CRTC216306228SIGNOR-249171
Regulator Mechanism/Effect Target SIGNOR-ID
SIK1phosphorylation
→
down-regulates activity 		CRTC2SIGNOR-249169
SIK3phosphorylation
→
down-regulates activity 		CRTC2SIGNOR-249171