| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | CEP55 | Ser428 | KVAASPKsPTAALNE | phosphorylation down-regulates | 16198290 | SIGNOR-140886 |
| MAPK1 | CEP55 | Ser425 | NREKVAAsPKSPTAA | phosphorylation down-regulates | 16198290 | SIGNOR-140890 |
| PLK1 | CEP55 | Ser436 | PTAALNEsLVECPKC | phosphorylation up-regulates | 16198290 | SIGNOR-140898 |
| MAPK1 | CEP55 | Ser428 | KVAASPKsPTAALNE | phosphorylation down-regulates | 16198290 | SIGNOR-140894 |
| CDK1 | CEP55 | Ser425 | NREKVAAsPKSPTAA | phosphorylation down-regulates | 16198290 | SIGNOR-140882 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | phosphorylation up-regulates → | CEP55 PSer428 | phosphorylation down-regulates ⊣ | CEP55 | 16198290 | SIGNOR-140886 |
| MAPK1 | phosphorylation up-regulates → | CEP55 PSer425 | phosphorylation down-regulates ⊣ | CEP55 | 16198290 | SIGNOR-140890 |
| PLK1 | phosphorylation up-regulates → | CEP55 PSer436 | phosphorylation up-regulates → | CEP55 | 16198290 | SIGNOR-140898 |
| MAPK1 | phosphorylation up-regulates → | CEP55 PSer428 | phosphorylation down-regulates ⊣ | CEP55 | 16198290 | SIGNOR-140894 |
| CDK1 | phosphorylation up-regulates → | CEP55 PSer425 | phosphorylation down-regulates ⊣ | CEP55 | 16198290 | SIGNOR-140882 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK1 | phosphorylation![]() down-regulates | CEP55 | SIGNOR-140886 |
| MAPK1 | phosphorylation![]() down-regulates | CEP55 | SIGNOR-140890 |
| PLK1 | phosphorylation → up-regulates | CEP55 | SIGNOR-140898 |
| MAPK1 | phosphorylation![]() down-regulates | CEP55 | SIGNOR-140894 |
| CDK1 | phosphorylation![]() down-regulates | CEP55 | SIGNOR-140882 |