| Name | PARP10 |
| ID | Q53GL7 |
| Role | substrate |
| Enzymatic Domains |
PARP catalytic 806-1025 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinE/CDK2 | PARP10 | Thr101 | QGLPPGTtPQRLEQH | phosphorylation up-regulates activity | 16455663 | SIGNOR-273594 |
| PLK1 | PARP10 | Thr601 | EVRELLAtLEGLDLD | phosphorylation up-regulates activity | 32060423 | SIGNOR-273728 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinE/CDK2 | phosphorylation up-regulates → | PARP10 PThr101 | phosphorylation up-regulates → | PARP10 | 16455663 | SIGNOR-273594 |
| PLK1 | phosphorylation up-regulates → | PARP10 PThr601 | phosphorylation up-regulates → | PARP10 | 32060423 | SIGNOR-273728 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinE/CDK2 | phosphorylation → up-regulates activity | PARP10 | SIGNOR-273594 |
| PLK1 | phosphorylation → up-regulates activity | PARP10 | SIGNOR-273728 |